Subtypes


Web

  • http://www.drugs.com/mtm/paclitaxel.html
  • Paclitaxel is a cancer medication that interferes with the growth and spread of cancer cells in the body.
  • http://chemocare.com/chemotherapy/drug-info/Paclitaxel.aspx
  • Paclitaxel is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.Paclitaxel is classified as a "plant alkaloid," a "taxane" and an "antimicrotubule agent."
  • http://www.cancer.gov/about-cancer/treatment/drugs/paclitaxel/
  • This page contains brief information about paclitaxel and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
  • http://www.nps.org.au/medicines/cancers/antimetabolites-chemother...
  • Abraxane Powder for injection is a brand of medicine containing the active ingredient paclitaxel, nab.
  • https://en.wikipedia.org/wiki/CT-2103
  • Paclitaxel is a drug used to treat ovarian, breast, lung, pancreatic and other cancers. [2] It and docetaxel represent the taxane family of drugs.
  • http://www.biospace.com/News/fda-approves-celgene-corporations-ab...
  • "The FDA approval of ABRAXANE is exciting for healthcare professionals because it offers an important new treatment option for all types of non-small cell lung cancer patients, in an area that has seen few treatment advancements in recent years." ...
  • http://www.oncolink.org/treatment/article.cfm?c=2&id=145&aid=430
  • Paclitaxel is a plant alkaloid that was developed from the bark of the Pacific Yew tree.
  • http://www.macmillan.org.uk/Cancerinformation/Cancertreatment/Tre...
  • During treatment, you usually see a cancer doctor, a chemotherapy nurse or a specialist nurse.
  • http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0082095/
  • In cases of prolonged neutropenia (> 7 days with ANC of < 0.5
  • http://www.myvmc.com/drugs/abraxane/
  • It is used to treat adult patients who have been unsuccessfully treated with anthracycline (another medicine used to treat metastatic breast cancer).
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    News

    A Comparison of Fucoidan Conjugated to Paclitaxel and Curcumin for the Dual Delivery of Cancer Therapeutic Agents
    Ingentaconnect - Saturday, January 12, 2019
    Brigatinib, paclitaxel, biosimilar pegfilgrastims receive EMA approvals
    Medwirenews - Thursday, October 11, 2018
    FDA Approves Eluvia Paclitaxel-Polymer Stent for PAD FDA Approves Eluvia Paclitaxel-Polymer Stent for PAD
    Med Worm - Thursday, September 27, 2018
    Oasmia Pharmaceutical Receives Positive CHMP Opinion for Apealea(R) (paclitaxel micellar) in the European Union
    EIN News - Friday, September 21, 2018
    nab-Paclitaxel plus carboplatin or gemcitabine versus gemcitabine plus carboplatin as first-line treatment of patients with triple-negative metastatic breast cancer: results from the tnAcity trial
    Bitly - Friday, August 17, 2018
    Study: Paclitaxel Best for HIV-Related Kaposi's Sarcoma
    Medpage Today - Thursday, August 2, 2018
    Phase III trial of nonpegylated liposomal doxorubicin in combination with trastuzumab and paclitaxel in HER2-positive metastatic breast cancer
    Oxford Journals - Sunday, July 29, 2018
    Global Paclitaxel Market 2018 Industry Key Players, Share, Trend, Segmentation and Forecast to 2023
    EIN Presswire - Tuesday, May 15, 2018
    Effects of Cryotherapy on Objective and Subjective Symptoms of Paclitaxel-Induced Neuropathy: Prospective Self-Controlled Trial
    Academic - Friday, February 16, 2018
    Sun Biopharma, Inc. Announces Initiation of First-Line Combination Study of Sbp-101 With Gemcitabine and Nab-Paclitaxel in Patients With Pancreatic Cancer
    P&T Community - Monday, January 29, 2018
    Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer
    Nature - Friday, January 26, 2018
    Everolimus With Trastuzumab and Paclitaxel for HER2+ MBC Everolimus With Trastuzumab and Paclitaxel for HER2+ MBC
    Med Worm - Wednesday, December 13, 2017
    No survival benefit with olaparib plus paclitaxel in advanced gastric cancer
    Medwirenews - Thursday, November 16, 2017
    A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer
    Nature - Thursday, November 9, 2017
    Identification of a peptide-peptide binding motif in the coating of nab-paclitaxel nanoparticles with clinical antibodies: bevacizumab, rituximab, and trastuzumab
    Nature - Friday, November 3, 2017
    A randomized, controlled phase III trial of nab -Paclitaxel versus dacarbazine in chemotherapy-na?ve patients with metastatic melanoma
    Oxford Journals - Friday, October 27, 2017
    Tripalmitin nanoparticle formulations significantly enhance paclitaxel antitumor activity against breast and lung cancer cells in vitro
    Nature - Wednesday, October 18, 2017
    The cancer chemotherapeutic agent paclitaxel (Taxol) reduces hippocampal neurogenesis via down-regulation of vesicular zinc
    Nature - Friday, September 15, 2017
    MORE NEWS

    Videos

    Abraxane Expanded To Treat Pancreatic Cancer Patients
         
    http://www.rxwiki.com/fda-alerts/abraxane-approved-treat-patients-pancreatic-cancer The FDA has expanded the approved uses of Abraxane to treat patients with late-stage pancreatic cancer. For more information, visit http://www.rxwiki.com/abraxane...

    ASCO 2010: Phase III clinical trials at ASCO 2010
         
    Prof Patrick Schöffski - Catholic University Leuven, Belgium Prof Schöffski talks about two phase III trial results presented at ASCO 2010. The first of these demonstrated that the tyrosine kinase inhibitor vandetanib increases progression free survi...

    Charles M. Perou, PhD, Discusses Genomic Signatures and Dual HER2-Targeting in Breast Cancer
         
    Charles M. Perou, PhD, professor of genetics, pathology & laboratory medicine, UNC Lineberger Comprehensive Cancer Center, discusses a trial (CALGB 40601) presented at the 2014 ASCO Annual Meeting that analyzed gene expression signatures in patients with ...

    How I made it through chemo ( fasting & chemo, plus tips & product recomendations)
         
  • I had Triple Negative Breast cancer these were some of my treatments: Beginning Oct 2011 - Dec 2011 I recieved 4 rounds 3 weeks apart of - 5FU , Epirubicin & Cytoxin Followed by Jan 2012 I received 3 weekly infusion of an abraxane (nabpacitaxol),1...

  • Combination of pazopanib and paclitaxel safe in urothelial cancer
           
    Prof Sandy Srinivas, (Stanford University Medical Centre, Stanford, USA) talks to ecancertv at ASCO GU 2015 about the results of a phase II study which looked at the use of pazopanib with weekly paclitaxel in refractory urothelial cancer.

    My experience with chemotherapy and its side effects ; MyOncofertility.org ; Fertility Preservation Options
           
    And then the second half

    Systemic Therapy for Stage IV Non-Small Cell Lung Cancer ; Cancer.Net
           
    The targeted therapy bevacizumab (Avastin) may be added to chemotherapy if a patient is receiving a combination of carboplatin (Paraplatin) and paclitaxel (Taxol).

    UPMC Physician Resources: Ongoing Clinical Trials
           
    UPCI 12-162: Phase 2, randomized, open-label study of MM-111 and paclitaxel with or without trastuzumab in patients with traditional and non-traditional HER2-expressing carcinomas of distal esophagus, gastroesophageal (GE) junction, and stomach who have

    Starve a Cancer, Stop Its Growth 14
           
    Starve a Cancer, Stop Its Growth: Advances in Anti-Angiogenesis 7) The role of Taxol therapy, based on recent clinical trials Response by: Daniel F. Hayes, MD Professor of Medicine, Director, Breast Oncology Program, University of Michigan, A...

    1 2 3 4 5 6 7 8 9

    Images

    Grinding Yew Bark for Paclitaxel
    Taxol(Paclitaxel)3D.png
    The bark is peeled and processed to provide paclitaxel.
    220px Tubulin paclitaxel 2HXF
    Paclitaxel, with rings labeled and accepted numbering scheme shown.
    Grinding Yew Bark for Paclitaxel
    cancer.gov
    Taxol(Paclitaxel)3D.png
    en.wikipedia.org
    The bark is peeled and processed to provide paclitaxel.
    en.wikipedia.org
    220px Tubulin paclitaxel 2HXF
    en.wikipedia.org
    Paclitaxel, with rings labeled and accepted numbering scheme shown.
    en.wikipedia.org
    Undisturbed Pacific yew bark contains paclitaxel and related chemicals.
    Space-filling model of paclitaxel
    Rotated paclitaxel molecule model
    108px Paclitaxel JMol Biol 2001 1045
    Molecular structure of paclitaxel.
    Undisturbed Pacific yew bark contains paclitaxel and related chemicals.
    en.wikipedia.org
    Space-filling model of paclitaxel
    en.wikipedia.org
    Rotated paclitaxel molecule model
    en.wikipedia.org
    108px Paclitaxel JMol Biol 2001 1045
    en.wikipedia.org
    Molecular structure of paclitaxel.
    en.wikipedia.org
    200px Paclitaxel JMol Biol 2001 1045
    Another representation of paclitaxel biosynthesis.
    Baccatin III (left) Paclitaxel (right)
    onxol 01
    abraxane 06
    200px Paclitaxel JMol Biol 2001 1045
    en.wikipedia.org
    Another representation of paclitaxel biosynthesis.
    en.wikipedia.org
    Baccatin III (left) Paclitaxel (right)
    en.wikipedia.org
    onxol 01
    drugs.com
    abraxane 06
    drugs.com
    abraxane 05
    Paclitaxel 100mg.jpg
    abraxane 03
    Paclitaxel structure.jpg
    abraxane 01
    abraxane 05
    drugs.com
    Paclitaxel 100mg.jpg
    wikidoc.org
    abraxane 03
    drugs.com
    Paclitaxel structure.jpg
    wikidoc.org
    abraxane 01
    drugs.com
    The adverse event profile for the patients who received Paclitaxel subsequent to AC was consistent with that seen in the pooled analysis of data from 812 patients (Table 10) treated with single-agent Paclitaxel in 10 clinical studies.
    The adverse event profile for patients receiving Paclitaxel in combination with cisplatin in these studies was qualitatively consistent with that seen for the pooled analysis of data from 812 patients treated with single-agent Paclitaxel in 10 clinical st
    Paclitaxel is a white to off-white crystalline powder with the molecular formula C47H51NO14 and a molecular weight of 853.9.
    NCI-funded research delivers a breakthrough discovery with paclitaxel (Taxol), a cancer drug from the bark of the Pacific yew tree that expands treatment options for patients with breast and ovarian cancers.
    With the discovery of the cancer drug paclitaxel (Taxol), patients with breast and ovarian cancers have hope for better treatment outcomes, increased life expectancy, and improved quality of life.
    The adverse event profile for the patients who received Paclitaxel subsequent to AC was consistent with that seen in the pooled analysis of data from 812 patients (Table 10) treated with single-agent Paclitaxel in 10 clinical studies.
    drugs.com
    The adverse event profile for patients receiving Paclitaxel in combination with cisplatin in these studies was qualitatively consistent with that seen for the pooled analysis of data from 812 patients treated with single-agent Paclitaxel in 10 clinical st
    drugs.com
    Paclitaxel is a white to off-white crystalline powder with the molecular formula C47H51NO14 and a molecular weight of 853.9.
    drugs.com
    NCI-funded research delivers a breakthrough discovery with paclitaxel (Taxol), a cancer drug from the bark of the Pacific yew tree that expands treatment options for patients with breast and ovarian cancers.
    cancer.gov
    With the discovery of the cancer drug paclitaxel (Taxol), patients with breast and ovarian cancers have hope for better treatment outcomes, increased life expectancy, and improved quality of life.
    cancer.gov
    Mansukh Wani, Ph.D., (left) and Monroe Wall, Ph.D., (right) discovered paclitaxel, a lifesaving compound from the bark of the Pacific yew tree.
    Tornado diagram of parameters to which the cost-effectiveness of paclitaxel versus PLDH is most sensitive (platinum resistant/refractory). pac, paclitaxel
    Tornado diagram of parameters to which the cost-effectiveness of trabectedin plus PLDH versus paclitaxel is most sensitive (PS network 2). pac, paclitaxel; Trab, trabectedin
    Tornado diagram of parameters to which the cost-effectiveness of PLDH versus paclitaxel is most sensitive (PS network 2). pac, paclitaxel
    Tornado diagram of parameters to which the cost-effectiveness of PLDH plus platinum versus paclitaxel plus platinum is most sensitive (PS network 1). pac, paclitaxel; plat, platinum
    Mansukh Wani, Ph.D., (left) and Monroe Wall, Ph.D., (right) discovered paclitaxel, a lifesaving compound from the bark of the Pacific yew tree.
    cancer.gov
    Tornado diagram of parameters to which the cost-effectiveness of paclitaxel versus PLDH is most sensitive (platinum resistant/refractory). pac, paclitaxel
    ncbi.nlm.nih.gov
    Tornado diagram of parameters to which the cost-effectiveness of trabectedin plus PLDH versus paclitaxel is most sensitive (PS network 2). pac, paclitaxel; Trab, trabectedin
    ncbi.nlm.nih.gov
    Tornado diagram of parameters to which the cost-effectiveness of PLDH versus paclitaxel is most sensitive (PS network 2). pac, paclitaxel
    ncbi.nlm.nih.gov
    Tornado diagram of parameters to which the cost-effectiveness of PLDH plus platinum versus paclitaxel plus platinum is most sensitive (PS network 1). pac, paclitaxel; plat, platinum
    ncbi.nlm.nih.gov
    Tornado diagram of parameters to which the cost-effectiveness of PLDH plus platinum versus platinum monotherapy is most sensitive (PS network 1). pac, paclitaxel; plat, platinum
    Chemical structure of paclitaxel.
    Cover of Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for advanced recurrent or refractory ovarian cancer: a systematic review and economic evaluation
    Adjusted Regimen of Abraxane and Gemzar Less Toxic in Pancreatic Cancer
    Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian
    Tornado diagram of parameters to which the cost-effectiveness of PLDH plus platinum versus platinum monotherapy is most sensitive (PS network 1). pac, paclitaxel; plat, platinum
    ncbi.nlm.nih.gov
    Chemical structure of paclitaxel.
    drugs.com
    Cover of Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for advanced recurrent or refractory ovarian cancer: a systematic review and economic evaluation
    ncbi.nlm.nih.gov
    Adjusted Regimen of Abraxane and Gemzar Less Toxic in Pancreatic Cancer
    curetoday.com
    Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian
    health.am
    You have paclitaxel and carboplatin through a drip into a vein once every 3 weeks.
    Study 2 was a multinational, randomized, double-blind study of Cyramza plus paclitaxel versus placebo plus paclitaxel that randomized (1:1) 665 patients with locally advanced or metastatic gastric cancer (including adenocarcinoma of the gastro-esophageal
    Paclitaxel Non-small cell lung trial.png
    Paclitaxel Metastatic breast cancer trial.png
    Paclitaxel FDA package label.png
    You have paclitaxel and carboplatin through a drip into a vein once every 3 weeks.
    cancerresearchuk.org
    Study 2 was a multinational, randomized, double-blind study of Cyramza plus paclitaxel versus placebo plus paclitaxel that randomized (1:1) 665 patients with locally advanced or metastatic gastric cancer (including adenocarcinoma of the gastro-esophageal
    drugs.com
    Paclitaxel Non-small cell lung trial.png
    wikidoc.org
    Paclitaxel Metastatic breast cancer trial.png
    wikidoc.org
    Paclitaxel FDA package label.png
    wikidoc.org

    MORE IMAGES