Subtypes


Web

  • http://www.drugs.com/mtm/trastuzumab.html
  • Trastuzumab is a cancer medication that interferes with the growth and spread of cancer cells in the body.
  • http://www.cancer.gov/about-cancer/treatment/drugs/trastuzumab/
  • This page contains brief information about trastuzumab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
  • http://www.cancerresearchuk.org/about-cancer/cancers-in-general/t...
  • Trastuzumab is a monoclonal antibody - a type of targeted treatment.
  • http://www.medicines.org.uk/emc/medicine/28168
  • 5. How to store Herceptin
  • http://www.nps.org.au/medicines/cancers/other-anticancer-medicine...
  • Herceptin Powder for infusion is a brand of medicine containing the active ingredient trastuzumab.
  • http://www.uwhealth.org/health/topic/multum/herceptin/d04357a1.html
  • Do not use trastuzumab if you are pregnant.It could harm the unborn baby.
  • http://www.oncolink.org/treatment/article.cfm?c=2&id=343&aid=608
  • Trastuzumab is a type of monoclonal antibody, which is a group of medications that are designed to target a specific type of cell (in this case, a Her2 positive breast or gastric cancer cell).
  • http://www.aetna.com/cpb/medical/data/300_399/0313.html
  • For individuals with breast cancer who are HER2-positive with no distant metastatic disease, up to 1 year of Herceptin is considered medically necessary for adjuvant treatment.
  • http://www.diagnosia.com/en/drug/herceptin-150-mg-powder-concentr...
  • Herceptin contains the active substance trastuzumab, which is a monoclonal antibody.
  • http://www.nhs.uk/Conditions/Herceptin/Pages/Introduction.aspx?ur...
  • Herceptin is the brand name of a medicine called trastuzumab.
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    News

    Trastuzumab Tied to Higher Long-Term Risk for Heart Failure
    Physicians Briefing - Wednesday, March 20, 2019
    Roadmap for the Development and Clinical Translation of Optical Tracers Cetuximab-800CW and Trastuzumab-800CW
    Snmjournals - Thursday, March 7, 2019
    Pfizer's Trastuzumab Biosimilar Noninferior in Two Breast Ca Trials
    Medpage Today - Thursday, February 7, 2019
    Trastuzumab Biosimilar Proves Mettle in Two Breast Ca Trials
    Medpage Today - Thursday, February 7, 2019
    Trastuzumab-Dttb Approved for Several Cancers
    P&T Community - Thursday, January 24, 2019
    miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells
    Nature - Thursday, January 24, 2019
    PF-05280014 (a trastuzumab biosimilar) plus paclitaxel compared with reference trastuzumab plus paclitaxel for HER2-positive metastatic breast cancer: a randomised, double-blind study
    Nature - Thursday, January 24, 2019
    Duration of adjuvant trastuzumab: might less be more?
    Doi - Saturday, January 12, 2019
    Nine weeks versus 1 year adjuvant trastuzumab in combination with chemotherapy: final results of the phase III randomized Short-HER study,
    Doi - Saturday, January 12, 2019
    Breast Cancer Patients Receiving Anthracycline Chemotherapy and Trastuzumab Have Biventricular Dysfunction and Reduced Heart Mass
    Medpage Today - Tuesday, December 18, 2018
    Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit
    Nature - Thursday, November 29, 2018
    Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab
    Doi - Sunday, November 11, 2018
    Genentech doses first patient in Perjeta and Herceptin Phase 3 study
    Drugdevelopment-Technology.com - Thursday, October 11, 2018
    Adding pertuzumab to trastuzumab effective for HER2-positive breast cancer
    Medwirenews - Wednesday, August 29, 2018
    Herceptin Tied to Heart Issues in Breast Ca Patients
    Medpage Today - Thursday, August 9, 2018
    Heart Monitoring a Must for Breast Cancer Patients on Herceptin
    Orlando Sentinel - Thursday, August 9, 2018
    Impact of timing of trastuzumab initiation on long-term outcome of patients with early-stage HER2-positive breast cancer: the "one thousand HER2 patients" project
    Nature - Thursday, August 2, 2018
    Can we establish a hierarchy among trastuzumab biosimilar candidates?
    Nature - Thursday, August 2, 2018
    MORE NEWS

    Videos

    Herceptin a Prescription Medication Used to Treat Breast and Stomach Cancer - Information
         
    http://www.rxwiki.com/herceptin https://www.youtube.com/watch?v=8q6iXxqUhQ4&list=PLXxn_pCvHVm7XKp6U5_K1B88bqvrJRjIg Herceptin is a prescription medication used to treat breast cancer and stomach cancer.  It may be used alone or in combination with ...

    SABCS: Trastuzumab Dosing During Chemo Vindicated
         
    http://www.medpagetoday.com SAN ANTONIO -- Delaying trastuzumab (Herceptin) until chemotherapy is finished may impair outcomes for women with breast cancer, researchers found. Women with HER2-positive cancer had a 25% better chance of disease-free s...

    Martine Piccart, MD, PhD: No Benefit in Extending Herceptin in HER2 Breast Cancer
         
    Dr. Martine Piccart sits down with Selma Schimmel and The Group Room at the 35th Annual CTRC-AACR San Antonio Breast Cancer Symposium (SABCS). They discuss the results of a study she authored for patients with human epidermal growth factor receptor 2 (HE...

    Herceptin for Biological and Targeted Therapies ; Dr. VK Gadi
         
    Dr. VK Gadi describes the use of biologic or targeted cancer treatment, including the use of Herceptin for HER2-positive breast cancer. Learn more at http://www.seattlecca.org/video-library.cfm Follow us on facebook https://www.facebook.com/SeattleC...

    Post-Op use of Herceptin, Part 2
         
    Response by Eduardo Cazap, Martine Piccart-Gebhart, Larry Norton, Alan Ashworth, comments by Clifford Hudis

    EBCC 7: Targeted therapy for breast cancer
         
    Dr Jones discusses the use of Trastuzumab (Herceptin) and Lapatinib as drugs to target the HER2 receptor and the possibility of combining these as part of a dual targeting approach, the drawbacks including side effects or resistance among patients and the...

    White Blood Cell Growth Factors ; Cancer.Net
         
  • Examples of these drugs include trastuzumab (Herceptin), lapatinib (Tykerb), pertuzumab (Perjeta), and ado-trastuzumab emtansine (Kadcyla), commonly referred to as T-DM1.

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    Images

    Trastuzumab Fab-HER2 complex 1N8Z.png
    1n8z: Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
    Trastuzumab emtansine.svg
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    Trastuzumab Fab-HER2 complex 1N8Z.png
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    1n8z: Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
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    Genentech Inc., the manufacturer of Herceptin, maintains a detailed website about Herceptin and HER2.
    WEDNESDAY Oct. 5, 2011 -- Treating women with an aggressive form of early stage breast cancer using Herceptin and chemotherapy, while not turning to a third type of drug known as an anthracycline, improves survival while posing less danger to the heart, r
    News Picture: Herceptin May Benefit Some Women With Early Breast Cancer
    The Mayo Clinic has identified genes that may help predict whether the drug trastuzumab will prevent the recurrence of breast cancer in some women, according to a study presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.
    herceptin 01
    drugs.com
    Genentech Inc., the manufacturer of Herceptin, maintains a detailed website about Herceptin and HER2.
    imaginis.com
    WEDNESDAY Oct. 5, 2011 -- Treating women with an aggressive form of early stage breast cancer using Herceptin and chemotherapy, while not turning to a third type of drug known as an anthracycline, improves survival while posing less danger to the heart, r
    drugs.com
    News Picture: Herceptin May Benefit Some Women With Early Breast Cancer
    medicinenet.com
    The Mayo Clinic has identified genes that may help predict whether the drug trastuzumab will prevent the recurrence of breast cancer in some women, according to a study presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium.
    healthline.com
    News Picture: Herceptin Best for Certain Breast Cancer Patients, Study Says
    SATURDAY Dec. 12, 2009 -- New research suggests that certain breast cancer patients who take the drug Herceptin during chemotherapy, instead of taking it afterward, fare better, leading one of the study authors to say patients should routinely take the dr
    Breast cancers that are HER2+ may respond to trastuzumab, which was one of the first types of targeted cancer drugs developed.
    Trastuzumab panel 02.png
    Trastuzumab panel 01.png
    News Picture: Herceptin Best for Certain Breast Cancer Patients, Study Says
    medicinenet.com
    SATURDAY Dec. 12, 2009 -- New research suggests that certain breast cancer patients who take the drug Herceptin during chemotherapy, instead of taking it afterward, fare better, leading one of the study authors to say patients should routinely take the dr
    drugs.com
    Breast cancers that are HER2+ may respond to trastuzumab, which was one of the first types of targeted cancer drugs developed.
    cancer.gov
    Trastuzumab panel 02.png
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    Herceptin Access Solutions
    Trastuzumab resistance: mechanisms and novel agents. (a) Trastuzumab (Tras) binds to the extracellular domain of HER2, but is incapable of disrupting the interaction of HER2 with other receptors such as EGFR.
    Outcome results with a median follow-up time of 2 years in 3351 patients with early-stage breast cancer treated with chemotherapy and randomized to the addition of trastuzumab or control. (a) The proportion of patients in each arm that remains cancer-free
    Diagram of how Herceptin may work
    Time 0 is initiation of paclitaxel or Herceptin + paclitaxel therapy.
    Herceptin Access Solutions
    herceptin.com
    Trastuzumab resistance: mechanisms and novel agents. (a) Trastuzumab (Tras) binds to the extracellular domain of HER2, but is incapable of disrupting the interaction of HER2 with other receptors such as EGFR.
    nature.com
    Outcome results with a median follow-up time of 2 years in 3351 patients with early-stage breast cancer treated with chemotherapy and randomized to the addition of trastuzumab or control. (a) The proportion of patients in each arm that remains cancer-free
    nature.com
    Diagram of how Herceptin may work
    herceptin.com
    Time 0 is initiation of paclitaxel or Herceptin + paclitaxel therapy.
    rxlist.com
    Synergistic effect of Ad-mda7 and Herceptin in Her-2+ breast cancer cells.
    Herceptin is a targeted therapy approved for the treatment of people with certain HER2+ cancers.
    How Herceptin may work MOA diagram
    Synergistic effect of Ad-mda7 and Herceptin in Her-2+ breast cancer cells.
    nature.com
    Herceptin is a targeted therapy approved for the treatment of people with certain HER2+ cancers.
    herceptin.com
    How Herceptin may work MOA diagram
    herceptin.com
    250px Trastuzumab Fab HER2 complex 1N8Z
    Schematic representation of trastuzumab emtansine.
    250px Trastuzumab Fab HER2 complex 1N8Z
    en.wikipedia.org
    Schematic representation of trastuzumab emtansine.
    en.wikipedia.org

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